Methods, systems and apparatuses, including computer programs encoded on computer storage media, are provided for monitoring a user's activity, orientation, and/or transitions between activities and/or orientations. A motion detection device is placed on a user's body in a manner to prevent the user from removing the device. The device detects the user's activities, orientations, and/or transitions via one or more accelerometers, gyroscopes, etc. The device transmits data regarding the activities, etc., to a server for logging and analysis. The data may be transmitted via a gateway device. Based on the analysis of the data, one or more notifications may be sent to, e.g., providers of the user. The motion detection device can detect that it has been removed from the user's body through a proximity detector, e.g., an infrared sensor. The motion detection device may include a button that can be pushed by a provider to indicate that a situation causing a notification, e.g., that the user has fallen, has been resolved.