The present invention relates to a kind of such as logical formula (I) compound represented; The compound has apoptosis signal regulating kinase (" ASK1 ") inhibitory activity, therefore available treatment of the what to diseases such as nephrosis, nephrosis and renal fibrosis.本發明涉及一種如通式(I)所示的化合物;該化合物具有細胞凋亡信號調節激酶(“ASK1”)抑制活性,因此可用於對腎病、糖尿病性腎病和腎臟纖維化等疾病的治療。