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Protected succinates for enhancing mitochondrial ATP-production
专利权人:
NEUROVIVE PHARMACEUTICALS AB
发明人:
Hans Georg Fliri,Rhonan Lee Ford,David Arthur Scowen,Derek Gregory Batcheller,Kari Henrik Johannes Ehinger,Mats Eskil Elmer,Magnus Joakim Hansson,Karl Fredrik Lennart Sjovall
申请号:
US14433558
公开号:
US09670175B2
申请日:
2013.10.04
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed herein are mono or di-succinate compounds where one or both of the acid groups in the succinate core are protected in the form of biologically labile moieties, and the use of said compounds to enhance mitochondrial function. The compounds may be of formula (I) wherein R1 is H or an optionally substituted alkyl group or a group of formula (II) and R2 is independently a group according to formula (II) where formula (II) is as defined 10 herein.
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