#$%^&*AU2016201333B220170907.pdf#####Examiners Abstract AU2016201333 A system and a computer program product comprising a non-transitory machine-readable medium storing instructions that, when executed by at least one programmable processor, cause the at least one programmable processor to perform operations comprising: receiving magnetic resonance imaging data captured by a magnetic resonance imaging system during radiation therapy of a patient during a treatment fraction, the magnetic resonance imaging data acquired at a rate sufficient to capture intra-fraction organ motions receiving data indicating ionizing radiation doses delivered to the patient and determining an actual dose deposition in the patient from the magnetic resonance imaging data and the delivered ionizing radiation doses data by summing doses delivered to the patient over at least a portion of the treatment fraction.