Andrea J. Bourdelais;Daniel G. Baden;Sophie Michelliza;William M. Abraham
发明人:
Daniel G. Baden,William M. Abraham,Andrea J. Bourdelais,Sophie Michelliza
申请号:
US13356312
公开号:
US20120122810A1
申请日:
2012.01.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are polycyclic polyether compounds of formula I and pharmaceutical compositions comprising such compounds.wherein R, OR1, and R2 are as defined herein.Also disclosed are methods of regulating mucus clearance in a cell, and methods of treating decreased mucus clearance or mucociliary dysfunction.