MYRIAD GENETICS, INC.;ABKEVICH, VICTOR;GUTIN, ALEXANDER;TIMMS, KIRSTEN;LANCHBURY, JERRY
发明人:
ABKEVICH, VICTOR,GUTIN, ALEXANDER,TIMMS, KIRSTEN,LANCHBURY, JERRY
申请号：
CA2860312
公开号：
CA2860312A1
申请日:
2012.12.21
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an LOH signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.
