Methods and materials for assessing homologous recombination deficiencies

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专利权人:

ミリアド・ジェネティックス・インコーポレイテッド

发明人:

アブケビック ビクター,ティムズ キルスティン,グティン アレクサンダー

申请号：

JP2016506657

公开号：

JP6625045B2

申请日:

2014.04.04

申请国别(地区):

JP

年份:

2019

代理人:

摘要：

This document provides methods and materials involved in assessing samples (eg, cancer cells) for the presence of homologous recombination deficiency (HRD) or HRD signature. For example, methods and materials are provided for determining whether a cell (eg, a cancer cell) contains an HRD signature. Materials and methods for identifying cells (eg, cancer cells) that are deficient in homologous recombination repair (HDR), and materials for identifying cancer patients who are likely to respond to a particular cancer treatment regimen and A method is also provided.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/