POLLARD, MATTHEW,KIENZLE, NORBERT ALEXANDER,CLARKE, ADAM WILLIAM,JENNINGS, PHILIP ANTHONY,DOYLE, ANTHONY GERARD
申请号：
NZ60091510
公开号：
NZ600915A
申请日:
2010.03.16
申请国别(地区):
NZ
年份:
2013
代理人:
摘要：
600915 Disclosed is a VH binding domain, the binding domain comprising a first framework region (EVQLQQWGAGLLKPSETLSLTCAVYGYSXX), a first CDR1 (SGYSWH), a second framework region(WIRQPPGKGLEWXG), a second CDR2 (HIHX8SGRPTYX9PSLX10S), a third framework region (RXXISXDTSKNQFSLKLSSVTAADTAVYYCAR), a third CDR3 (KGKGSDDGLNY) and a fourth framework region (WGQGTLVTVSS). Alternatively disclosed is a VL binding domain, the binding domain comprising a first framework region (EXVLTQSPATLSLSPGERATLSC), a first CDR1 (SASSSLSYIH), a second framework region (WYQQKPGQAPRLLIY), a second CDR2 (DTSNLAS), a third framework region (GIPDRFSGSGSGXDFTLTISRLEPEDFAVYYC), a third CDR3 (FQGSEYPLT) and a fourth framework region (FGGGTKVEIKR).
