Universite Paris Descartes;Ce;Universite Paris-Sud;Institut national de la sante et de la recherche medicale (Inserm);Universite Pierre et Marie Curie (Paris 6);Assistance Publique - Hopitaux de Paris
A present invention relates to isolated peptides obtained from human fibrinogen for their use as drug, particularly for the prevention and/or the treatment of inflammatory skin diseases, more particularly acne. The present invention also relates to fragments of these polypeptides, nucleic acid molecules encoding them, expression vectors, host cells, a pharmaceutical composition and a combination product containing them, and their use for treating and/or preventing inflammatory skin diseases, particularly acne.