Alexey Alexandrovic Lugovskoy;Herman Van Vlijmen;Karl J. M. Hanf
发明人:
Herman Van Vlijmen,Alexey Alexandrovic Lugovskoy,Karl J. M. Hanf
申请号：
US11572647
公开号：
US08647625B2
申请日:
2005.07.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides peptides, and fragments thereof, and antibodies, or fragments thereof comprising the same, wherein the peptide comprises at least one amino acid substitution compared to wild type 5c8 antibody. The present invention also provides compositions and methods of treating CD154-related diseases or disorders in a subject.
