Keith L. Haney;Lawrence Chew;Jeffrey Allen;Ping-Hua Feng;Anant Patkar;Lei Lei Phokham Sengchanthalangsy
发明人:
Jeffrey Allen,Ping-Hua Feng,Anant Patkar,Keith L. Haney,Lawrence Chew,Lei Lei Phokham Sengchanthalangsy
申请号：
US13039183
公开号：
US09187543B2
申请日:
2011.03.02
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to the field of recombinant protein production in bacterial hosts. It further relates to extraction of soluble, active recombinant protein from an insoluble fraction without the use of denaturation and without the need for a refolding step. In particular, the present invention relates to a production process for obtaining high levels a soluble recombinant Type 1 interferon protein from a bacterial host.
