The present invention provides a method for purifying retinal pigment epithelial cells capable of obtaining retinal pigment epithelial cells of high purity in a short period of time from a cell group obtained by inducing differentiation of pluripotent stem cells into retinal pigment epithelial cells in a simple operation Method. The purification method of the present invention includes a step of introducing a cell group containing retinal pigment epithelial cells obtained by differentiating pluripotent stem cells on laminin or a fragment thereof into a filter to obtain a cell group that has passed through the filter .本発明は、多能性幹細胞からの網膜色素上皮細胞への分化誘導により得られる細胞群から、簡易な操作で高い純度の網膜色素上皮細胞を短期間で得ることができる網膜色素上皮細胞の純化方法を提供する。本発明の純化方法は、多能性幹細胞をラミニンまたはそのフラグメント上で分化誘導して得られた網膜色素上皮細胞を含む細胞群をフィルターに導入し、フィルターを通過した細胞群を得る工程を含む。