A new and distinct cultivar of Poinsettia plant named ‘PER508’, characterized by its compact, uniform, upright and mounded plant habit； moderately vigorous growth habit； freely and upright branching habit； very dark green-colored leaves with sinuate margins that give the leaves a textured appearance； under natural season conditions, plants flower on or about December 5 in Southern California； large inflorescences with burgundy-colored flower bracts； and good post-production longevity.
