A new and distinct cultivar of Poinsettia plant named ‘；PER1549’；, characterized by its moderately compact, uniform, upright and mounded plant habit； moderately vigorous growth habit； freely and upright to somewhat outwardly branching habit； dark green-colored leaves； under natural season conditions, plants flower on or about November 25 in Southern California； large inflorescences with bright yellow to yellow orange-colored flower bracts； and good post-production longevity.
