Paul N. Durfee;Charles Jeffrey Brinker;Kimberly Butler
发明人:
Charles Jeffrey Brinker,Kimberly Butler,Paul N. Durfee
申请号：
US16490280
公开号：
US20200009264A1
申请日:
2018.03.01
申请国别(地区):
US
年份:
2020
代理人:
摘要：
In one aspect, the disclosure provides mesoporous silica nanoparticles (MSNPs), monodisperse populations of MSNPs and related protocells which exhibit cell binding specificity. For example, MSNPs and protocells of the disclosure may be used to target specific delivery of therapeutic agents to CD19 or EGFR expressing cancer cells, or target specific delivery of therapeutic agents to other cell types. Related protocells, pharmaceutical compositions and therapeutic and diagnostic methods are also provided.
