Charles Jeffrey Brinker,Jason TOWNSON,Yu-Shen LIN,Paul N. DURFEE,BRINKER, Jeffrey, C.,TOWNSON, Jason,LIN, Yu-Shen,DURFEE, Paul, N.
申请号：
US15023093
公开号：
US20160287717A1
申请日:
2014.09.18
申请国别(地区):
US
年份:
2016
代理人:
摘要：
In one aspect, the invention provides mesoporous silica nanoparticles (MSNPs), monodisperse populations of MSNPs and related protocells which exhibit single cell binding specificity to the substantial exclusion of non-targeted cells. For example, MSNPs and protocells of the invention may be used to target specific delivery of therapeutic agents to cancer cells or to specific blood vessel types (e.g. in the arterial, venous and/or capillary vessels or any combination of vessels). Related protocells, pharmaceutical compositions and therapeutic and diagnostic methods are also provided.
