ZHANG, LEI,LACHAPELLE, ERIK ALPHIE,BUTLER, CHRISTOPHER RYAN,KABLAOUI, NATASHA MARIAM,BRODNEY, MICHAEL AARON,MCALLISTER, LAURA ANN,YANG, QINGYI,HELAL, CHRISTOPHER JOHN,WEBB, DAMIEN
申请号：
CA3094366
公开号：
CA3094366A1
申请日:
2019.03.25
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention provides, in part, compounds of Formula I: or an N- oxide thereof, or a pharmaceutically acceptable salt of the compound or the N-oxide, wherein: X1, X2, R1, R2, m and n are as described herein； processes for the preparation of； intermediates used in the preparation of； and compositions containing such compounds, N-oxides, or salts, and their uses for treating M4-mediated (or M4-associated) disorders including, e.g., Alzheimer's Disease, Parkinson's Disease, schizophrenia (e.g., its cognitive and negative symptoms), pain, addiction, and a sleep disorder.
