The invention relates to a embedding particle for embedding lactobacillus with ganoderma mycelium, which comprises a Lactobacillus core, a colloidal material layer and a ganoderma mycelium shell layer, the colloidal material layer covers the Lactobacillus core, and the ganoderma mycelium shell layer covers the colloidal material layer.Using the ganoderma mycelium shell and the gelatinous material layer as the embedding structure, it can effectively protect the activity of the Lactobacillus before entering the digestive system of the organism and not affected by the surrounding environment, so that the lactobacillus can reach the small intestine and the large intestine smoothly. In addition, the embedding particles have better acid resistance, bile salt resistance and pepsin resistance than the traditional freeze-dried powder.一種以靈芝菌絲包埋乳酸菌之包埋顆粒，包含一乳酸菌核、一膠狀物質層以及一靈芝菌絲殼層，該膠狀物質層包覆該乳酸菌核，而該靈芝菌絲殼層包覆該膠狀物質層。利用該靈芝菌絲殼層和該膠狀物質層作為包埋結構，可有效保護乳酸菌在進入生物體的消化系統前，保有其活性且不受週遭環境影響，使乳酸菌能順利到達小腸及大腸，此外，該包埋顆粒較傳統冷凍乾燥粉具較佳之耐酸、耐膽鹽、耐胃蛋白酶特性。
