The present technology relates to an information processing apparatus, an information processing method, and a program that can improve the estimation accuracy of a motion amount of an object.A cross-correlation analysis unit performs a cross-correlation analysis between a first image and a second image obtained by capturing the same object as an object of the first image before the first image, a first motion estimation unit estimates a first motion amount corresponding to a motion blur in the first image, and a second motion estimation unit estimates a second motion amount different from the first motion amount between the first image and the second image on the basis of a result of the cross-correlation analysis and an estimation result of the first motion amount. The present technology can be applied to, for example, an apparatus for measuring a pulse.