Mark T. Bilodeau,Mary Simcox,Brian H. White,Sudhakar Kadiyala,Richard Wooster
申请号：
US16093233
公开号：
US20200078468A1
申请日:
2017.04.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Conjugates of an active agent attached to a neurotensin receptor-binding targeting moiety via a linker have been designed. Nanoparticles and microparticles comprising such conjugates can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer or other diseases.
