An ultraviolet sterilization and disinfection device, which is mainly provided with a recess on a housing, at least one ultraviolet irradiation lamp and at least one photosensitive element are arranged in the recess, and at least one control circuit, a buzzer and A compulsory start-up module, through which the ultraviolet sterilization and disinfection device can be forced to activate the ultraviolet irradiation lamp to sterilize the place to be disinfected when the photosensitive element detects the external light. Before activating the ultraviolet radiation lamp, a buzzer is used to warn the user to avoid the line of sight and to avoid exposing the skin exposed to the clothing to the ultraviolet radiation range.一種紫外線殺菌消毒裝置,其主要是在一殼體上設置有一凹部,該凹部內設有至少一紫外線照射燈及至少一光敏元件,且該殼體內設有至少一控制電路、一蜂鳴器及一強制開機模組,透過該強制開機模組,可令紫外線殺菌消毒裝置在光敏元件偵測到外界光的狀態下,強制啟動紫外線照射燈對欲消毒的地方進行紫外線殺菌之動作,同時在強制啟動紫外線照射燈前,利用蜂鳴器告警,而令使用者避開視線,及避免將裸露在衣物外的皮膚暴露在紫外線照射範圍內。