Mabry, Thomas Edward,Li, Renhua,Anzeveno, Peter Biagio,Tian, Hongqi,Xu, Yanping,Saeed, Ashraf,Snyder, Nancy June,Aicher, Thomas Daniel,Stephenson, Gregory Alan,Wallace, Owen Brendan,Krasutsky, Alexei
申请号:
AU2007240550
公开号:
AU2007240550B2
申请日:
2007.04.05
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention discloses novel compounds of Formula (I): having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I), as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11β-HSD type 1 activity.