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Flexible carbohydrate-bearing polymer
专利权人:
Jesper Svenning Kristensen
发明人:
Jesper Svenning Kristensen,Klaus Gregorius,Casper Struve,Yihua Yu
申请号:
US12085961
公开号:
US08691517B2
申请日:
2006.12.06
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A sensor for the detection or measurement of a carbohydrate analyte in fluid comprises components of a competitive binding assay the readout of which is a detectable or measurable optical signal retained by a material that permits diffusion of the analyte but not the assay components, the assay components comprising: a carbohydrate binding molecule labelled with one of a proximity based signal generating/modulating moiety pair and a carbohydrate analogue capable of competing with the analyte for binding to the carbohydrate binding molecule, the carbohydrate analogue being a flexible water-soluble polymer comprising: polymerized or co-polymerised residues of monomer units, the monomer unit residues bearing pendant carbohydrate or carbohydrate mimetic moieties and pendant moieties which are the other of the proximity based signal generating/modulating moiety pair.
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