Compositions and methods for treating hyperlipidemia and elevated LDL cholesterol and for weight reduction are disclosed. The compositions comprise(a) choline, or a salt or hydroxide thereof(b) niacin, or a salt, amide or ester thereof(c) folic acid, or a salt thereof(d) methionine or a salt or ester thereof and(e) glycine or a salt, ester or methylated form thereof.
