J. Mark BRAUGHLER;Walter J. Storkus;Hideho Okada;Prasanna Kumar
发明人:
J. Mark BRAUGHLER,Prasanna Kumar,Walter J. Storkus,Hideho Okada
申请号:
US13224091
公开号:
US20120114620A1
申请日:
2011.09.01
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention provides the field of therapeutics. Most specifically present invention provides methods of generating in vitro engineered dendritic cells conditionally expressing interleukin-12 (IL-12) under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals including human.