UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION;INTREXON CORPORATION
发明人:
HIDEHO OKADA,MARK J. BRAUGHLER,PRASANNA KUMAR,WALTER J. STORKUS
申请号：
BRPI0818287
公开号：
BRPI0818287A2
申请日:
2008.10.08
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
This invention provides the field of therapeutics. Most specifically present invention provides methods of generating in vitro engineered dendritic cells conditionally expressing interleukin-12 (IL- 12) under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals including human.
