De Graaff, Wouter,Veenstra, Harm,Mulders, Titia Martine Truce
申请号:
AU2010244494
公开号:
AU2010244494B2
申请日:
2010.05.03
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
An intrauterine system (1) is disclosed for use in the treatment of dysfunctional uterine bleeding; menorraghia; dysmenorrhoea; endometriosis; uterine fibroids; climacteric complaints; osteoporosis; and urogenital atrophy. The system is formed by a frame (16) defining an interior space (20) for receipt of a deposit (22) of a therapeutically effective dose of a biologically active compound. The frame has an open structure allowing access to a substantial part of an outer surface of the deposit, and the deposit has a rate controlling structure (26) that controls a rate of release of the compound within the uterus. One or more retention elements (6) are provided on the frame for retaining the frame within the uterus of a female mammal.