The present invention relates to a use of type II mucin in manufacturing a pharmaceutical composition for promoting cell proliferation, skin regeneration, and wound healing. A pharmaceutical composition comprising type II mucin for promoting cell proliferation, skin regeneration, and wound healing is also provided.本發明係有關於一種第二型黏液蛋白質於製備促進細胞生長、皮膚再生及傷口癒合醫藥組合物之用途。本發明亦提供一種用於促進細胞生長、皮膚再生及傷口癒合之包含第二型黏液蛋白質之醫藥組合物。