An apparatus or method for forming a sterile connection. The apparatus includes at least two sterile tubes each disposed within a flange. Each flange has an external face that completely covers the mouth of the tube. Each flange is designed to be displaced when force is applied to the tube to move the tubes toward one another such that the external face of each flange is displaced radially or axially outwards away from the mouth of the tube. When the external faces are displaced, the external face of each flange opens and tubes connect and form a sterile connection therebetween.一種用以形成一無菌連接的裝置或方法。該裝置包含至少二無菌的管各設在一凸緣內。各凸緣具有一外正面會完全地覆蓋該管的口部。各凸緣係被設計成當力被施加於該管來朝向彼此移動該等管時能被移位，而使各凸緣的外正面會徑向或軸向地朝外移位離開該管的口部。當該等外正面移位時，各凸緣的外正面會打開且管會連接而在其間形成一無菌連接。
