It treats ultrasonic system transmitting staggeredly or the treatment wave beam of interlacing pattern is to be used for the treatment that ultrasound thrombolysis is mediated with other blood vessel acoustic resonators (VAR). The technology of the present invention due to adjacent beams destruction and minimize the VAR of such as microvesicle, by ensuring the uniform sonication to target area with the space between subsequent transmitting filling wave beam, and the device for steeping supplement is additionally provided so that the clot dissolution because of ultrasound maximizes. The drug delivery and Blood Brain Barrier (BBB) opening that the technology is also applied for diagnostic ultrasound, VAR is mediated.
