The present invention relates to time capsules, vessels or containers, in particular but not limited to a permanently sealable non-reusable time capsule, vessel or container for storing a biological sample containing DNA for a prolonged period of time. The time capsule comprising a thick-walled vessel or container having a void or chamber with a tapered entry adapted to house glass vials containing the item of interest, a plug having a complementary external tapered configuration corresponding to the tapered entry, the tapered plug and entry having opposed peripheral grooves that are aligned when the plug is positioned in the vessel and a hard setting compound used to seal the plug forms a keyed ring in the opposing grooves to permanently and hermetically seal the plug in the vessel.