MARTINEZ, IGNACIO,ARMEN, ZACHARY GARO,MARTIN, BARRY ANDREW,AVENDANO AMADO, MAIER STEVE
申请号：
CA3046614
公开号：
CA3046614A1
申请日:
2018.01.24
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Provided herein are agents, compositions, and methods useful for animal health, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host insect (e.g., arthropod, e.g., insect, e.g., pathogen vector), the alteration resulting in a decrease in the fitness of the host. The invention features a composition that includes an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, or microbial diversity, the agents described herein may be used to decrease the fitness of a variety of insects that carry vector-borne pathogens that cause disease in animals.
