PHENANTHROINDOLIZIDINE DERIVATIVE AND NFkB INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT

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专利权人:

KABUSHIKI KAISHA YAKULT HONSHA

发明人:

IKEDA, TAKASHI,SAWADA, SEIGO,YAEGASHI, TAKASHI,MATSUZAKI, TAKESHI,HASHIMOTO, SHUSUKE,YAMAZAKI, RYUTA

申请号：

NZ59242909

公开号：

NZ592429A

申请日:

2009.10.23

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed herein are phenanthiroindolizidine derivatives of formula (I), wherein the substituents are as defined within the specification, processes for its preparation, compositions comprising said compounds and uses thereof. Said compounds are useful as Nuclear Factor-êB (NFêB) inhibitors and is therefore useful in the treatment of diseases associated with accelerated NFêB activity, such as cancer.

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