The present invention relates to a pharmaceutical composition for treating diabetes, containing metformin and a DPP-TV inhibitor. The pharmaceutical composition for treating diabetes according to the present invention can cut off the contact between the DPP-TV inhibitor and metformin, so that the lifespan of the composition is increased and the amount as well as the kind of a flexible material contained in the composition is reduced. Furthermore, the DPP-TV inhibitor can be rapidly released and the sustained-release of metformin can be controlled.本發明涉及包含二甲雙胍和二肽基肽酶4 (dipeptidyl peptidase 4， DPP-IV）抑制劑的糖尿病治療用藥劑學組合物。本發明的糖尿病治療用藥劑學組合物可以阻斷二肽基肽酶4抑制劑與二甲雙胍之間的接觸，因而具有增加有效期，並減少存在於組合物內的雜質的種類及其量的優點。與此同時，具有既可以迅速釋放二肽基肽酶4抑制劑，又可以調節二甲雙胍的緩釋型釋放。
