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ЭМУЛЬСИИ ДЛЯ МИКРОКАПСУЛИРОВАНИЯ, СОДЕРЖАЩИЕ БИОРАЗЛАГАЕМЫЕ ПОВЕРХНОСТНО-АКТИВНЫЕ БЛОК-СОПОЛИМЕРЫ В КАЧЕСТВЕ СТАБИЛИЗАТОРОВ
专利权人:
ЕВОНИК КОРПОРЕЙШН (US)
发明人:
МАРКЛЭНД Питер (US)
申请号:
RU2012145462/15
公开号:
RU2012145462A
申请日:
2011.03.25
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. An emulsion comprising an external continuous phase of the first liquid and an inner discontinuous phase of the second fluid, which is at least partially miscible with the first liquid wherein the emulsion further comprises: (a) a biodegradable surface active block copolymer comprising one or more hydrophilic units and one or more hydrophobic blocks (B) a biodegradable encapsulating polymer, and (c) a biologically active agent.2. Emulsion according to claim 1, wherein the inner discontinuous phase or outer continuous phase comprises at least 0.001 mg / l of the surfactant block sopolimera.3. Emulsion according to claim 1, wherein the inner discontinuous phase or outer continuous phase comprises at least 0.1 mg / l of the surfactant block sopolimera.4. Emulsion according to claim 1, wherein the inner discontinuous phase or outer continuous phase comprises from 0.1 mg / l to 10 mg / l surfactant block sopolimera.5. Emulsion according to claim 1, characterized in that a biodegradable surface active block copolymer is neionnym.6. Emulsion according to claim 1, characterized in that the surface-active block copolymer comprising one or more blocks of hydrophilic poly (ethylene glycol) (PEG), poly (vinylpyrrolidone) (PVP) or a polysaccharide and one or more hydrophobic block of poly (lactide), poly (glycolide), poly (caprolactone), poly (valerolactone), poly (hydroxybutyrate) or sopolimer.7. Emulsion according to claim 1, characterized in that one or more blocks of hydrophilic surface-active block copolymer has a molecular weight of from 250 to 20,000 Daltons (Da) .8. Emulsion according to claim 1, characterized in that one or more blocks of hydrophilic surfactants1. Эмульсия, содержащая внешнюю непрерывную фазу первой жидкости и внутреннюю дисперсную фазу второй жидкости, которая по меньшей мере частично не смешивается с первой жидкостью где эмульсия дополнительно содержит: (а) биоразлагаемый поверхностно-активный блок-сополимер, содержащий один или более гидрофильных
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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