PROBLEM TO BE SOLVED: To provide a new intracerebral β-endorphin production promoting agent combinable with formulation perfumes, seasonings, processed foods, beverages, luxury goods, cosmetics, aromatics, deodorants, detergents, bath liquids, miscellaneous goods, vaporization aspiration preparations, quasi drugs, pharmaceuticals, compositions for external use or fibers.SOLUTION: This intracerebral β-endorphin production promoting agent contains a phenol derivative represented by formula (I). In the formula (I), R1 is HO- or CH3O-, R2 and R3 are each independently a group selected from a group comprising H-, HO-, and CH3O- (wherein, at least either of R2 and R3 is CH3O-), and R is a group selected from a group comprising H-, CH3O-, 1-4C alkyl group and 1-4C alkenyl group.COPYRIGHT: (C)2013,JPO&INPIT【課題】調合香料、調味料、加工食品、飲料、嗜好品、化粧品、芳香剤、消臭剤、洗浄剤、浴剤、雑貨類、気化吸引用剤、医薬部外品、医薬品、外用組成物、又は繊維に配合することができる、新たな脳内β-エンドルフィン産生促進剤の提供。【解決手段】下記式(I)で表されるフェノール誘導体を含む脳内β-エンドルフィン産生促進剤。式(I)中、R1はHO-又はCH3O-であり、R2及びR3はそれぞれ独立にH-、HO-及びCH3O-からなる群より選ばれた基(但し、R2及びR3の少なくとも一方はCH3O-である)であり、RはH-、CH3O-、炭素数1~4のアルキル基及び炭素数1~4のアルケニル基からなる群より選ばれた基である。【選択図】なし
