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DETECTION DE L'ACTIVATION DU COMPLEMENT
专利权人:
KYPHA; INC.
发明人:
OLSON, PAUL,MOSS, DONALD W.,STATEN, NICK
申请号:
CA2871910
公开号:
CA2871910A1
申请日:
2013.04.30
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Methods of detecting complement activation including steps of detecting in a sample from a subject a level of iC3b wherein the detecting involves specific interaction between the iC3b and a non-cross-reactive antibody thereto, comparing the detected level with a reference level, which reference level is within a range of about 10 ng/ml to about 5,000 ng/ml, wherein determination that the detected level is above the reference level indicates that the subject is suffering from or susceptible to undesirable and/or pathologic complement activation, and administering treatment to treat undesired complement activation if the detected level is above the reference level. Other methods of detecting complement activation with or without measuring iC3b are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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