A method, apparatus, and system acquire data to create a 3D mesh representing a 3D object. The method, apparatus, and system acquire image data of the 3D object using two probes of an imaging system. The flexible probes conform to the shape of the 3D object, illuminate the object at a face of each probe head via optical fibers coupled to an illumination system, and receive at the surface of the 3D object, via optical fibers coupled to a detection system, light reflected from and/or transmitted through the 3D object. The reflectance and transillumination image data collected by the detection system are co-registered with the previously acquired 3D mesh using data from a tracking system monitoring the position of each probe, displayed in real-time, and optionally saved.