ALILA, Hector,LEUSCHNER, Carola,JUBAN, Martha,COULTER, Ann
申请号：
USUS2011/034338
公开号：
WO2011/137245A3
申请日:
2011.04.28
申请国别(地区):
WO
年份:
2012
代理人:
摘要：
Disclosed are conjugates comprising a ligand that binds to Her2/neu. The ligand comprises polypeptides including growth factors, hormones, antibodies, and antibody fragments. The disclosure also provides methods of using the conjugates that bind to Her2/neu for treating disorders associated with undesirable or aberrant cell proliferation including hyperproliferative disorders, such as tumors, cancers, neoplasia and malignancies that express Her2/neu.Linvention concerne des conjugués se liant à Her2/neu, des méthodes dutilisation des conjugués se liant à Her2/neu et des méthodes de traitement de la prolifération cellulaire indésirable ou aberrante ou des troubles hyperprolifératifs, tels que les tumeurs, les cancers, la néoplasie et les tumeurs malignes exprimant Her2/neu.
