ZUSAMMENSETZUNGEN ZUR TRANSFEKTION VON RESISTENTEN ZELLTYPEN

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专利权人:

Precision Nanosystems Inc

发明人:

THOMAS, Anitha,DE SOUZA, Rebecca Anne Grace,OUELLET, Eric,THARMARAJAH, Grace Tharmini,SINGH, Jagbir,GARG, Shyam Madhusudan

申请号：

EP17857727

公开号：

EP3519578A4

申请日:

2017.10.02

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

A transfection reagent composition comprising: 30-60 MOL. % of a cationic lipid, or a pharmaceutical acceptable salt thereof； 10-60 MOL % of a structural lipid； 10-20 MOL % of a triglyceride； and 0.1 to about 10 MOL. % of a stabilizing agent, is provided. The transfection agent is effective in transfecting cells, particularly neurons, with siRNA, mRNA and plasmid nucleic acid, Sand maintaining viability of the cells as well as activity of the delivered nucleic acid.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/