The present invention relates to compounds of general formulaI,wherein the groups R1, R2and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity.本發明係關於通式I之化合物,其中基團R1、R2及n如技術方案1中所定義,該等化合物具有有價值的藥理學特性,尤其與飢餓素O-醯基轉移酶(GOAT)結合且調節其活性。該等化合物適用於治療及預防可受此受體影響之疾病,諸如代謝疾病,尤其肥胖。