A METHOD OF TREATING TRIPLE NEGATIVE BREAST CANCER IN A MAMMAL COMPRISING THE STEP OF: ADMINISTERING TO A PATIENT A PHARMACEUTICAL ACCEPTABLE AMOUNT OF A COMPOUND BEING A THIENOTRIAZOLODIAZEPINE COMPOUND OF THE FORMULA (1) WHEREIN R IS ALKYL HAVING A CARBON NUMBER OF 1 4 R IS A HYDROGEN ATOM A HALOGEN ATOM OR ALKYL HAVING A CARBON NUMBER OF 1 4 OPTIONALLY SUBSTITUTED BY A HALOGEN ATOM OR A HYDROXYL GROUP R IS A HALOGEN ATOM PHENYL OPTIONALLY SUBSTITUTED BY A HALOGEN ATOM ALKYL HAVING A CARBON NUMBER OF 1 4 ALKOXY HAVING A CARBON NUMBER OF 1 4 OR CYANO NR (CH) R WHEREIN R IS A HYDROGEN ATOM OR ALKYL HAVING A CARBON NUMBER OF 1 4 M IS AN INTEGER OF 0 4 AND R IS PHENYL OR PYRIDYL OPTIONALLY SUBSTITUTED BY A HALOGEN ATOM OR NR CO (CH) R WHEREIN R IS A HYDROGEN ATOM OR ALKYL HAVING A CARBON NUMBER OF 1 4 N IS AN INTEGER OF 0 2 AND R IS PHENYL OR PYRIDYL OPTIONALLY SUBSTITUTED BY A HALOGEN ATOM AND R IS (CH) CO NH R WHEREIN A IS AN INTEGER OF 1 4 AND R IS ALKYL HAVING A CARBON NUMBER OF 1 4 HYDROXYALKYL HAVING A CARBON NUMBER OF 1 4 ALKOXY HAVING A CARBON NUMBER OF 1 4 OR PHENYL OR PYRIDYL OPTIONALLY SUBSTITUTED BY ALKYL HAVING A CARBON NUMBER OF 1 4 ALKOXY HAVING A CARBON NUMBER OF 1 4 AMINO OR A HYDROXYL GROUP OR (CH) COORWHEREIN B IS AN INTEGER OF 1 4 AND R IS ALKYL HAVING A CARBON NUMBER OF 1 4 OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF OR A HYDRATE OR SOLVATE THEREOF IN COMBINATION WITH ONE OR MORE CHEMOTHERAPY DRUGS SELECTED FROM THE GROUP CONSISTING OF M TOR INHIBITORS AND MITOTIC INHIBITORS.
