593264 Provided is an extract of aerial part(s) of oats harvested before ear emergence characterized by 2 to 15 % of flavonoids and 0.2 to 2% of avenacosides A and B and comprising less than 1 ppm of proteins obtained by acetone extraction. An oat extract can also be obtained by using one or more of acetone, methylethylketone, methylisobutylketone, ethyl acetate and a C1-C4 alcohol. The compositions are useful to manufacture medicaments for treating acne, dermatosis and psoriasis or as an anti-aging cosmetic for skin.