A fluorescence observation endoscope system includes a light source apparatus configured to include one light emitting body configured to be able to emit light in a first wavelength band which is radiated onto medicine administered to a living body to thereby emit fluorescence, light in a second wavelength band and light in a third wavelength band, a light guide, an image pickup section configured to include an image pickup device to simultaneously receive the fluorescence and reflected light of the light in the second and third wavelength bands, and a signal processing apparatus configured to generate color display images from an image pickup signal of the fluorescence and second and third image pickup signals acquired from the reflected light of the light in the second and third wavelength bands.
