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Low molecular weight branched polyamines for delivery of biologically active materials
专利权人:
Wei Cheng;Amanda C. Engler;Chuan Yang;Pei Yun Teo;James L. Hedrick;Daniel J. Coady;Yi Yan Yang
发明人:
Wei Cheng,Daniel J. Coady,Amanda C. Engler,James L. Hedrick,Pei Yun Teo,Chuan Yang,Yi Yan Yang
申请号:
US13613353
公开号:
US09109087B2
申请日:
2012.09.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A branched polyamine comprises about 8 to about 12 backbone tertiary amine groups, about 18 to about 24 backbone secondary amine groups, a positive number n′ greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2):wherein (n′+q) is a number equal to about 8 to about 12, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L′ is a divalent linking group comprising 3 to 30 carbons, and q/(n′+q)×100% equals about 9% to about 40%.
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