1. A composition comprising: a. Cynara extracts, with the content of the coffee-quinic acid ranging from 30 to 45% by weight, the content of flavonoids in the range of from 8 to 16% by weight and the content tsinaropikrina in the range from 10 to 18% by weight b. extract of Coffea spp, the content of the coffee-quinic acid ranging from 40% to 80% by weight. c. extract Olea europaea, with a content of polyphenols ranging from 30% to 40% at a concentration verbaskozida higher than 5%, and the concentration of hydroxytyrosol is higher than 1.5% .2. Composition according to Claim. 1, where Cynara extract has a content of the coffee-quinic acid of 35 ± 2% by weight, the content of flavonoids 12 ± 2% by weight and the content tsinaropikrina 13 ± 2% vesu.3. Composition according to Claim. 1, wherein the extract Coffea spp. preferably it has a coffee-quinic acid of 60 ± 2% by vesu.4. Composition according to claim. 1, where Olea europaea extract has a polyphenol content of 30 ± 2% verbaskozida a concentration higher than 5%, and the concentration of hydroxytyrosol is higher than 1.5% .5. A composition according to claim. 1-4, where Cynara extract is an extract of Cynara scolymus or Cynara cardunculus.6. A composition according to claim. 1-4, wherein the extract Coffea spp. It is an extract of Coffea arabica.7. A composition according to claim. 1-4, wherein the weight ratio of extract of Cynara extracts and Coffea spp. Olea europaea and is in the range from 0.5 to 2.8. A composition according to claim. 7 wherein the amount of Cynara extract, Coffea arabica and Olea europaea extract is within the range from 100 to 300 mg.9. A composition according to claim. 1-4 for use in the pharmacological treatment of metabolic sindroma.10. A composition according to claim. 1-4 for use in the pharmacological treatment of diabetes mellitus type 2.11. A composition according to claim. 1-4 for use in the pharmacological treatment of hyperglycemia, hypercholesterolemia, hypertension and ozhire