COMPOSE DE PYRIMIDINE OU DE PYRIDOPIRYDINE ET UTILISATION EN TANT QU'INHIBITEURS DE KINASE DEPENDANTE DES CYCLINES

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专利权人:

GUANGZHOU BEBETTER MEDICINE TECHNOLOGY CO.; LTD.

发明人:

CAI, XIONG,QIAN, CHANGGENG,LI, JUNQI,QING, YUANHUI,WANG, YANYAN,XUE, WEICAI,YOU, HUAJIN

申请号：

CA3000548

公开号：

CA3000548A1

申请日:

2016.05.31

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention discloses a pyrimidine or pyridopyridone compound as shown in formula (I) and an application thereof relating to the technical field of medicament preparation. The compound can selectively suppress cyclin-dependent kinases (Cdks) CFK4 and CDK6 with almost no suppression of the activity of the kinase CDK2. Thus, the compound can be used for various diseases caused by cell cycle control disorders involving CDK4 and CDK6, and particularly in the treatment of malignant tumors.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/