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A LABELING PRECURSOR COMPOUND AND METHOD FOR PRODUCING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME
专利权人:
NIHON MEDI-PHYSICS CO.; LTD.
发明人:
申请号:
EP16186503.5
公开号:
EP3141537B1
申请日:
2016.08.31
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide a simple purification method of a radioactive fluorine labeled compound and a labeled precursor compound.SOLUTION: There is provided a labeled precursor compound represented by the formula (2), where R1 is an alkyl group, an aryl group, a nitrogen-containing heterocycle or the like, R2 and R3 are a hydroxy alkyl group of which an alkyl group or a hydroxyl group are protected with a protection group or unprotected, n is an integer of 1 to 2, R6 is an alkyl group or a -CONR11R12 group, R11 and R12 are each independently an alkyl group or a substituted/unsubstituted monocyclic or condensed polycyclic aryl group and R4, R5, R7 and R8 are each independently H, an alkyl group or the like.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT
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