DEUTERATED IMIDAZO[4,5-C]QUINOLIN-2-ONE COMPOUNDS AND THEIR USE IN TREATING CANCER

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专利权人:

ASTRAZENECA AB

发明人:

PIKE, Kurt,BARLAAM, Bernard

申请号：

SG11201908065Y

公开号：

SG11201908065YA

申请日:

2018.03.15

申请国别(地区):

SG

年份:

2019

代理人:

摘要：

I) C O () INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 20 September 2018 (20.09.2018) WIP0 I PCT omit VIII °nolo omioomi oviiiin mom ois (10) International Publication Number WO 2018/167203 Al (51) International Patent Classification: TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, CO7D 471/04 (2006.01) A61P 35/00 (2006.01) KM, ML, MR, NE, SN, TD, TG). A61K 31/437 (2006.01) (21) International Application Number: PCT/EP2018/056516 Declarations under Rule 4.17: as to applicant's entitlement to apply for and be granted a patent (Rule 4.1700) (22) International Filing Date: 15 March 2018 (15.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/472,080 16 March 2017 (16.03.2017) US (71) Applicant: ASTRAZENECA AB [SE/SE]； 151 85 Sodertalje (SE). (72) Inventors: PIKE, Kurt, Gordon； AstraZeneca, Dar- win Building, Cambridge Science Park, Milton Road, Cambridge CB4 OWG (GB). BARLAAM, Bernard, Christophe； AstraZeneca, Darwin Building, Cambridge Science Park, Milton Road, Cambridge Cambridgeshire CB4 OWG (GB). = (74) Agent: NESS, Mark, David； AstraZeneca Intellectual Property, Milstein Building, Granta Park, Cambridge CB21 6GH (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection a

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