Baker Heart and Diabetes Institute;Washington State University
发明人:
RODGERS, Buel, Dantese,GREGOREVIC, Paul
申请号:
EP16784014
公开号:
EP3285813A4
申请日:
2016.04.22
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Described herein are vectors, such as adeno-associated virus (AAV) vectors, and recombinant AAV expressing Smad7. The disclosed AAV vectors and rAAV can be used for therapeutic applications in the treatment and amelioration of muscle wasting, cardiac and/or skeletal muscle wasting associated with cancer cachexia.